Our research activity focuses on the development of advanced molecular diagnostics technologies and point-of-care devices for early detection and management of diseases. Our highly multidisciplinary research activities combine the fundamental and translational studies at the interface between chemistry, physics, nanotechnology, and biology, with the aim of -
- substantially improving performance of current disease diagnosis and management strategies by developing simple, sensitive and low cost molecular diagnostics methods/devices
- generating breakthroughs in fundamental sciences
The Shiddiky Laboratory is pursuing studies of the development of multifunctional magnetic nanomaterials based novel nanomachineries for the highly selective isolation and sensitive detection of exosome and exosomal biomarkers in patients with cancer and other diseases.
The Shiddiky Laboratory is working on the development of novel technologies and POC diagnostic methods to detect diseases at the time and place of patient care using minimal specialised infrastructure.
A novel platform method based on metal-biomolecules affinity interaction (i.e., adsorption) for the analysis of a range of genetic, epigenetic, and proteomic biomarkers in patients with cancers and other diseases. This method can overcome the major technological drawbacks in current biosensing approaches.
The Shiddiky Laboratory focuses to develop portable devices and technologies for ‘on-farm’ analysis of pathogen species and pathogenic biomarkers in unprocessed plant extracts. Such a device would allow more rapid and cost-effective detection, control and management of the plant diseases.
